Replicacion de los virus rna

Miembro prototipo: poliovirus figuras 1 y 2. Las nuevas cadenas de sentido negativo sirven como plantilla para nuevas cadenas de sentido positivo figura 5. La nueva cadena de sentido positivo tiene 3 destinos alternativos : i.

Puede ser empacada en los viriones progenie iii. Los viriones se liberan luego de la lisis celular. Cuerpo de Negri. Rabdovirus yemando. Ejemplo: Virus de la rabia. El virus fijado es engullido por endocitosis. Los ARNm son chapados, metilados, y poliadenilados. Ser empacadas en los viriones. Virus sincitial respiratorio. Se basa en la habilidad del virus para unirse a receptores en los eritrocitos.

Esto es usado como plantilla para cadenas completas en sentido negativo. Figura Ortomixovirus figuras 16 y Arenavirus figura 19b.

Hay tres grupos de virus influenza: A, B y C. Hay ocho segmentos de ARN en el virus de la influenza A. Esto es muy inusual para un virus de ARN. Por ejemplo, el segmento M resulta en dos ARNm alternativos. Los ARNm son traducidos en el citoplasma. N ota :. No segmentado. Necesidad de un iniciador de ARN. Hemaglutinina, neuraminidasa. La familia de los reovirus incluye:. El Virus de la Fiebre de Garrapata de Colorado. Zinsser Microbiology 2O ava.

Hay diferencias significativas en el ciclo de vida de los miembros de las familias reovirus y rotavirus. Replication: After the viral genome has been uncoated, transcription or translation of the viral genome is initiated.

It is this stage of viral replication that differs greatly between DNA and RNA viruses and viruses with opposite nucleic acid polarity. This process culminates in the de novo synthesis of viral proteins and genome. Assembly: After de novo synthesis of viral genome and proteins, which can be post-transrciptionally modified, viral proteins are packaged with newly replicated viral genome into new virions that are ready for release from the host cell.

This process can also be referred to as maturation. Virion release: There are two methods of viral release: lysis or budding. Lysis results in the death of an infected host cell, these types of viruses are referred to as cytolytic. An example is variola major also known as smallpox.

Enveloped viruses, such as influenza A virus, are typically released from the host cell by budding. It is this process that results in the acquisition of the viral phospholipid envelope. These types of virus do not usually kill the infected cell and are termed cytopathic viruses. Residual viral proteins that remain within the cytoplasm of the host cell can be processed and presented at the cell surface on MHC class-I molecules, where they are recognised by T cells.

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